Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells.

Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells.

PC12 cells are a well-established model to study how differences in signal transduction duration can elicit distinct cell behaviors. Epidermal growth factor (EGF) activates transient ERK signaling in PC12 cells that lasts 30-60 min, which in turn promotes proliferation; nerve growth factor (NGF) act...

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Bibliographic Details
Main Authors: Kenneth W Adams, Sergey Kletsov, Ryan J Lamm, Jessica S Elman, Steven Mullenbrock, Geoffrey M Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5226839?pdf=render

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http://europepmc.org/articles/PMC5226839?pdf=render

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