Identification of active compounds in Vernonia anthelmintica (L.) willd by targeted metabolome MRM and kaempferol promotes HaCaT cell proliferation and reduces oxidative stress

Identification of active compounds in Vernonia anthelmintica (L.) willd by targeted metabolome MRM and kaempferol promotes HaCaT cell proliferation and reduces oxidative stress

Introduction:Vernonia anthelmintica (L.) Willd. is a traditional treatment for vitiligo in Xinjiang. However, its therapeutic mechanism remains unclear owing to its complex composition and limited research on its chemical profile.Methods: We employed a targeted metabolome approach, combining selecti...

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Bibliographic Details
Main Authors: Wen Hu, Hongjuan Wang, Kaixiao Li, Zixian Lei, Fang Xiang, Jun Li, Xiaojing Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Pharmacology
Subjects:
vitiligo
Vernonia anthelmintica
kaempferol
PI3K/AKT signaling
HaCaT cell
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1343306/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1343306/full

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