Probucol promotes osteoblasts differentiation and prevents osteoporosis development through reducing oxidative stress

Abstract Probucol (PBC) is a potent cholesterol-lowering drug and has been studied extensively for its powerful antioxidative stress. The purpose of this study is to investigate the role of PBC in ovariectomized rat model and to explore the mechanism of osteogenic differentiation of MC3TE-E1 Cells....

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Bibliographic Details
Main Authors: Zhou-Shan Tao, Tian-Lin Li, Shan Wei
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-022-00503-7