Evaluation of Heterocyclic Carboxamides as Potential Efflux Pump Inhibitors in <i>Pseudomonas aeruginosa</i>

Evaluation of Heterocyclic Carboxamides as Potential Efflux Pump Inhibitors in <i>Pseudomonas aeruginosa</i>

The ability to rescue the activity of antimicrobials that are no longer effective against bacterial pathogens such as <i>Pseudomonas aeruginosa</i> is an attractive strategy to combat antimicrobial drug resistance. Herein, novel efflux pump inhibitors (EPIs) demonstrating strong potentia...

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Bibliographic Details
Main Authors: Yi Yuan, Jesus D. Rosado-Lugo, Yongzheng Zhang, Pratik Datta, Yangsheng Sun, Yanlu Cao, Anamika Banerjee, Ajit K. Parhi
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Antibiotics
Subjects:
<i>Pseudomonas aeruginosa</i>
RND efflux pumps
efflux pump inhibitors
heterocyclic carboxamides
antimicrobial drug resistance
Online Access:https://www.mdpi.com/2079-6382/11/1/30

Internet

https://www.mdpi.com/2079-6382/11/1/30

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