YM115, A PHARMACOLOGICAL SUPPRESSANT OF SURVIVIN/XIAP, EXHIBITS ANTINEOPLASTIC ACTIVITY IN JAK2V617F CELLS
Objective: The central role of the control of apoptosis in the pathophysiology of Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) has been recently reinforced in genetic and pharmacological studies. The inhibitor of apoptosis protein (IAP) family has eight members and plays an im...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137923006314 |