The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus

The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus

Summary: Monoclonal antibodies against the Ebola virus (EBOV) surface glycoprotein are effective treatments for EBOV disease. Antibodies targeting the EBOV glycoprotein (GP) head epitope have potent neutralization and Fc effector function activity and thus are of high interest as therapeutics and fo...

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Bibliographic Details
Main Authors: Xiaoying Yu, Kathryn M. Hastie, Carl W. Davis, Ruben Diaz Avalos, Dewight Williams, Diptiben Parekh, Sean Hui, Colin Mann, Chitra Hariharan, Ayato Takada, Rafi Ahmed, Erica Ollmann Saphire
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723013785

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http://www.sciencedirect.com/science/article/pii/S2211124723013785

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