Transcription factor BACH1 in cancer: roles, mechanisms, and prospects for targeted therapy

Abstract Transcription factor BTB domain and CNC homology 1 (BACH1) belongs to the Cap ‘n’ Collar and basic region Leucine Zipper (CNC-bZIP) family. BACH1 is widely expressed in mammalian tissues, where it regulates epigenetic modifications, heme homeostasis, and oxidative stress. Additionally, it i...

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Main Authors: Dian Hu, Zerui Zhang, Xiangyuan Luo, Siwen Li, Junqing Jiang, Jiaqian Zhang, Zhangfan Wu, Yijun Wang, Mengyu Sun, Xiaoping Chen, Bixiang Zhang, Xiao Xu, Shuai Wang, Shengjun Xu, Yufei Wang, Wenjie Huang, Limin Xia
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Biomarker Research
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Online Access:https://doi.org/10.1186/s40364-024-00570-4