Genetic Variation in MicroRNA-423 Promotes Proliferation, Migration, Invasion, and Chemoresistance in Breast Cancer Cells

Genetic Variation in MicroRNA-423 Promotes Proliferation, Migration, Invasion, and Chemoresistance in Breast Cancer Cells

MicroRNA-423 (miR-423) is highly expressed in breast cancer (BC). Previously, our group showed that the SNP rs6505162:C>A located in the pre-miR-423 was significantly associated with increased familial BC risk in patients with a strong family history of BC. Therefore, in this study, we evaluated...

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Bibliographic Details
Main Authors: Sebastian Morales-Pison, Lilian Jara, Valentina Carrasco, Cristian Gutiérrez-Vera, José Miguel Reyes, Patricio Gonzalez-Hormazabal, Leandro J. Carreño, Julio C. Tapia, Héctor R. Contreras
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
microRNA function
microRNA-423
functional study
Online Access:https://www.mdpi.com/1422-0067/23/1/380

Internet

https://www.mdpi.com/1422-0067/23/1/380

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