One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams

One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams

The Friedel–Crafts reaction of novel 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones was used for low cost, one-pot preparation of polycyclic indole derivatives structurally similar to Ergot alkaloids.

Bibliographic Details
Main Authors: Vladimir T. Abaev, Nicolai A. Aksenov, Dmitrii A. Aksenov, Elena V. Aleksandrova, Alesia S. Akulova, Igor A. Kurenkov, Alexander V. Leontiev, Alexander V. Aksenov
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
polycyclic indoles
intramolecular Friedel–Crafts reaction
cascade transformations
Online Access:https://www.mdpi.com/1420-3049/28/7/3162

Internet

https://www.mdpi.com/1420-3049/28/7/3162

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