Mouse DRG Cell Line with Properties of Nociceptors.

In vitro cell lines from DRG neurons aid drug discovery because they can be used for early stage, high-throughput screens for drugs targeting pain pathways, with minimal dependence on animals. We have established a conditionally immortal DRG cell line from the Immortomouse. Using immunocytochemistry...

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Bibliographic Details
Main Authors: Ciara Doran, Jonathan Chetrit, Matthew C Holley, David Grundy, Mohammed A Nassar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0128670