Serum SNTF, a Surrogate Marker of Axonal Injury, Is Prognostic for Lasting Brain Dysfunction in Mild TBI Treated in the Emergency Department

Serum SNTF, a Surrogate Marker of Axonal Injury, Is Prognostic for Lasting Brain Dysfunction in Mild TBI Treated in the Emergency Department

Mild traumatic brain injury (mTBI) causes persisting post-concussion syndrome for many patients without abnormalities on conventional neuroimaging. Currently, there is no method for identifying at-risk cases at an early stage for directing concussion management and treatment. SNTF is a calpain-deriv...

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Bibliographic Details
Main Authors: Robert Siman, Hongmei Cui, Sandi S. Wewerka, Lydia Hamel, Douglas H. Smith, Michael D. Zwank
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neurology
Subjects:
mild traumatic brain injury
prognostic biomarker
diffuse axonal injury
blood test
post-concussion syndrome
calpain
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00249/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00249/full

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