Preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates

Preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates

Abstract COVID-19 outbreak caused by SARS-CoV-2 created an unprecedented health crisis since there is no vaccine for this novel virus. Therefore, SARS-CoV-2 vaccines have become crucial for reducing morbidity and mortality. In this study, in vitro and in vivo safety and efficacy analyzes of lyophili...

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Bibliographic Details
Main Authors: Gozde Sir Karakus, Cihan Tastan, Derya Dilek Kancagi, Bulut Yurtsever, Gamze Tumentemur, Sevda Demir, Raife Dilek Turan, Selen Abanuz, Didem Cakirsoy, Utku Seyis, Samed Ozer, Omer Elibol, Muhammer Elek, Gurcan Ertop, Serap Arbak, Merve Acikel Elmas, Cansu Hemsinlioglu, Ayse Sesin Kocagoz, Ozden Hatirnaz Ng, Sezer Akyoney, Ilayda Sahin, Ugur Ozbek, Dilek Telci, Fikrettin Sahin, Koray Yalcin, Siret Ratip, Ercument Ovali
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83930-6

Internet

https://doi.org/10.1038/s41598-021-83930-6

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