Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly

Self-assembly of ESCRT-III complex is a critical step in all ESCRT-dependent events. ESCRT-III hetero-polymers adopt variable architectures, but the mechanisms of inter-subunit recognition in these hetero-polymers to create flexible architectures remain unclear. We demonstrate in vivo and in vitro t...

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Bibliographic Details
Main Authors: Sudeep Banjade, Shaogeng Tang, Yousuf H Shah, Scott D Emr
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/46207