Clone dissemination of IncX3 plasmid carrying blaNDM-1 in ST76 carbapenem resistance Klebsiella pneumoniae and bactericidal efficiency of aztreonam combined with avibactam in vitro and in vivo

Clone dissemination of IncX3 plasmid carrying blaNDM-1 in ST76 carbapenem resistance Klebsiella pneumoniae and bactericidal efficiency of aztreonam combined with avibactam in vitro and in vivo

Objectives: The rapid spread of the New Delhi Metal-β-lactamase-1 (NDM-1) gene in Klebsiella pneumoniae poses a substantial challenge to pediatric therapeutic care. Here, we aimed to characterise the IncX3-type plasmid carrying the blaNDM-1 gene in ST76 carbapenem resistance K. pneumoniae (CRKP) str...

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Bibliographic Details
Main Authors: Tianqun Huo, Ziyan Kong, Guokai Dong, Shulong Zhao, Xuemei Liu, Fei Jiang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
St76 klebsiella pneumoniae
Blandm-1
Incx3 plasmid
Aztreonam/Avibactam
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716524000067

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http://www.sciencedirect.com/science/article/pii/S2213716524000067

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