The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus

The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus

The regulation of the nucleocytoplasmic release of herpesviral capsids is defined by the process of nuclear egress. Due to their large size, nuclear capsids are unable to traverse via nuclear pores, so that herpesviruses evolved to develop a vesicular transport pathway mediating their transition thr...

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Bibliographic Details
Main Authors: Sigrun Häge, Nicole Büscher, Victoria Pakulska, Friedrich Hahn, Annie Adrait, Steffi Krauter, Eva Maria Borst, Ursula Schlötzer-Schrehardt, Yohann Couté, Bodo Plachter, Manfred Marschall
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
human cytomegalovirus
regulation of viral replication
nuclear egress complex (NEC)
NEC protein pUL50
functional properties
conditional expression
Online Access:https://www.mdpi.com/2073-4409/10/11/3119

Internet

https://www.mdpi.com/2073-4409/10/11/3119

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