Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets

Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets

Abstract Background Systemic sclerosis (SSc) is a rare autoimmune fibrosing disease with an incompletely understood genetic and non-genetic etiology. Defining its etiology is important to allow the development of effective predictive, preventative, and therapeutic strategies. We conducted this epige...

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Bibliographic Details
Main Authors: Paula S. Ramos, Kip D. Zimmerman, Sandra Haddad, Carl D. Langefeld, Thomas A. Medsger, Carol A. Feghali-Bostwick
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Clinical Epigenetics
Subjects:
Systemic sclerosis
DNA methylation
Genome
Blood
Twins
Online Access:http://link.springer.com/article/10.1186/s13148-019-0652-y

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http://link.springer.com/article/10.1186/s13148-019-0652-y

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