The Role of Eryptosis in the Pathogenesis of Renal Anemia: Insights From Basic Research and Mathematical Modeling

Red blood cells (RBC) are the most abundant cells in the blood. Despite powerful defense systems against chemical and mechanical stressors, their life span is limited to about 120 days in healthy humans and further shortened in patients with kidney failure. Changes in the cell membrane potential and...

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Bibliographic Details
Main Authors: Gabriela Ferreira Dias, Nadja Grobe, Sabrina Rogg, David J. Jörg, Roberto Pecoits-Filho, Andréa Novais Moreno-Amaral, Peter Kotanko
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.598148/full