Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy

Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy

BackgroundPrevious studies suggested involvement of non-ß-adrenoceptors in the pathogenesis of Takotsubo cardiomyopathy (TTC). This study was designed to explore possible roles and underlying mechanisms of dopamine D1/D5 receptor coupled signaling in arrhythmogenesis of TTC.MethodsHuman-induced plur...

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Bibliographic Details
Main Authors: Mengying Huang, Zhen Yang, Yingrui Li, Huan Lan, Lukas Cyganek, Goekhan Yuecel, Siegfried Lang, Karen Bieback, Ibrahim El-Battrawy, Xiaobo Zhou, Martin Borggrefe, Ibrahim Akin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Takotsubo cardiomyopathy
arrhythmia
catecholamine excess
D1/D5 dopamine receptor
human-induced pluripotent stem cell-derived cardiomyocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.777463/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.777463/full

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