The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis

The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis

Proinflammatory chemokine ligand 26 (CCL26, eotaxin-3) mediates transendothelial cell migration of eosinophils by binding and activating the G-protein-coupled (GPC) chemokine receptor 3 on the surface of eosinophilic cells. Here we have investigated the role of glycosaminoglycans (GAGs) as potential...

Full description

Bibliographic Details
Main Authors: Alexandra Pum, Maria Ennemoser, Tanja Gerlza, Andreas J. Kungl
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
CCL26
eotaxin-3
glycosaminoglycans
GAG
heparan sulfate
heparinase C
Online Access:https://www.mdpi.com/1422-0067/23/12/6519

Internet

https://www.mdpi.com/1422-0067/23/12/6519

Similar Items