Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice

Abstract Antigenically distinct SARS-CoV-2 variants increase the reinfection risk for vaccinated and previously exposed population due to antibody neutralization escape. COVID-19 severity depends on many variables, including host immune responses, which differ depending on genetic predisposition. To...

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Bibliographic Details
Main Authors: Gagandeep Singh, Juan García-Bernalt Diego, Prajakta Warang, Seok-Chan Park, Lauren A. Chang, Moataz Noureddine, Gabriel Laghlali, Yonina Bykov, Matthew Prellberg, Vivian Yan, Sarabjot Singh, Lars Pache, Sara Cuadrado-Castano, Brett Webb, Adolfo García-Sastre, Michael Schotsaert
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54334-7