Sesquiterpene lactones-enriched fractions from Xanthium mongolicum Kitag alleviate RA by regulating M1 macrophage polarization via NF-κB and MAPK signaling pathway

Sesquiterpene lactones-enriched fractions from Xanthium mongolicum Kitag alleviate RA by regulating M1 macrophage polarization via NF-κB and MAPK signaling pathway

Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease, characterized by activated M1-like macrophage in the joint. Xanthium mongolicum Kitag (X. mongolicum) is a traditional medicinal plant that has long been used to treat RA and other immune diseases in China.Methods: Fractions of...

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Bibliographic Details
Main Authors: Jing Han, Jingwen Wang, Yicun Wang, Zhiqi Zhu, Siwang Zhang, Bingrong Wu, Mingsong Meng, Jianning Zhao, Dongsheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
Xanthium mongolicum kitag
sesquiterpene lactone
macrophage
traditional Chinese medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1104153/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1104153/full

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