Dexamethasone suppresses the differentiation of stem Leydig cells in rats in vitro

Dexamethasone suppresses the differentiation of stem Leydig cells in rats in vitro

Abstract Background It is an established fact that excess of glucocorticoids could cause the harmful effects, such as suppression on the male reproduction. Although glucocorticoids pharmacologically inhibit the Leydig cell function, their roles in Leydig cell development are unclear. Therefore, the...

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Bibliographic Details
Main Authors: Jingwei Zhang, Guanghui Hu, Bisheng Huang, Dong Zhuo, Yujie Xu, Huitao Li, Xiangcheng Zhan, Ren-Shan Ge, Yunfei Xu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Pharmacology and Toxicology
Subjects:
Glucocorticoid
Dexamethasone
Stem Leydig cells
Proliferation
Differentiation
Testosterone
Online Access:http://link.springer.com/article/10.1186/s40360-019-0312-z

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http://link.springer.com/article/10.1186/s40360-019-0312-z

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