Prognostic and Predictive Value of Three DNA Methylation Signatures in Lung Adenocarcinoma

Prognostic and Predictive Value of Three DNA Methylation Signatures in Lung Adenocarcinoma

Background: Lung adenocarcinoma (LUAD) is the leading cause of cancer-related mortality worldwide. Molecular characterization-based methods hold great promise for improving the diagnostic accuracy and for predicting treatment response. The DNA methylation patterns of LUAD display a great potential a...

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Bibliographic Details
Main Authors: Yanfang Wang, Haowen Deng, Shan Xin, Kai Zhang, Run Shi, Xuanwen Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
LUAD
DNA methylation
regularized logistic regression
recursive feature elimination
LASSO Cox regression
metastasis
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00349/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00349/full

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