The population impact of herpes simplex virus type 2 (HSV-2) vaccination on the incidence of HSV-2, HIV and genital ulcer disease in South Africa: a mathematical modelling studyResearch in context

The population impact of herpes simplex virus type 2 (HSV-2) vaccination on the incidence of HSV-2, HIV and genital ulcer disease in South Africa: a mathematical modelling studyResearch in context

Summary: Background: Evidence suggests HSV-2 infection increases HIV acquisition risk and HIV/HSV-2 coinfection increases transmission risk of both infections. We analysed the potential impact of HSV-2 vaccination in South Africa, a high HIV/HSV-2 prevalence setting. Methods: We adapted a dynamic H...

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Bibliographic Details
Main Authors: Jack Stone, Katharine Jane Looker, Romain Silhol, Katherine Mary Elizabeth Turner, Richard Hayes, Jenny Coetzee, Stefan Baral, Sheree Schwartz, Philippe Mayaud, Sami Gottlieb, Marie-Claude Boily, Peter Vickerman
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:EBioMedicine
Subjects:
HSV-2
HIV
Vaccine
Mathematical modelling
South Africa
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423000956

Internet

http://www.sciencedirect.com/science/article/pii/S2352396423000956

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