Fibroblast activation protein-based theranostics in pancreatic cancer

Fibroblast activation protein-α (FAP) is a type II transmembrane serine protease that has specific endopeptidase activity. Given its well-established selective expression in the activated stromal fibroblasts of epithelial cancers, although not in quiescent fibroblasts, FAP has received substantial r...

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Bibliographic Details
Main Authors: Chien-shan Cheng, Pei-wen Yang, Yun Sun, Shao-li Song, Zhen Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.969731/full