Network-based analysis of differentially expressed genes in cerebrospinal fluid (CSF) and blood reveals new candidate genes for multiple sclerosis

Network-based analysis of differentially expressed genes in cerebrospinal fluid (CSF) and blood reveals new candidate genes for multiple sclerosis

Background The involvement of multiple genes and missing heritability, which are dominant in complex diseases such as multiple sclerosis (MS), entail using network biology to better elucidate their molecular basis and genetic factors. We therefore aimed to integrate interactome (protein–protein inte...

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Bibliographic Details
Main Authors: Nahid Safari-Alighiarloo, Mostafa Rezaei-Tavirani, Mohammad Taghizadeh, Seyyed Mohammad Tabatabaei, Saeed Namaki
Format: Article
Language:English
Published: PeerJ Inc. 2016-12-01
Series:PeerJ
Subjects:
Protein–protein interaction network (PPIN)
Transcriptome
Topology
Modularity
Clique analysis
Multiple sclerosis
Online Access:https://peerj.com/articles/2775.pdf

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https://peerj.com/articles/2775.pdf

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