Synthesis and Biological Evaluation of Novel Benzothiazole Derivatives as Potential Anticonvulsant Agents

New benztriazoles with a mercapto-triazole and other heterocycle substituents were synthesized and evaluated for their anticonvulsant activity and neurotoxicity by using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ), and rotarod neurotoxicity (TOX) tests. Among the compound...

Description complète

Détails bibliographiques
Auteurs principaux: Da-Chuan Liu, Hong-Jian Zhang, Chun-Mei Jin, Zhe-Shan Quan
Format: Article
Langue:English
Publié: MDPI AG 2016-02-01
Collection:Molecules
Sujets:
Accès en ligne:http://www.mdpi.com/1420-3049/21/3/164