A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording

A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording

High-throughput screening (HTS) using ion channel recording is a powerful drug discovery technique in pharmacology. Ion channel recording with planar bilayer lipid membranes (BLM) is scalable and has very high sensitivity. A HTS system based on BLM ion channel recording faces three main challenges:...

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Bibliographic Details
Main Authors: Marco Crescentini, Marco Bennati, Shimul Chandra Saha, Josip Ivica, Maurits de Planque, Hywel Morgan, Marco Tartagni
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Sensors
Subjects:
transimpedance amplifier
current sensing circuit
low-noise amplifier
low-noise current sensor
noise
ion channel recording
bilayer lipid membranes
electrophysiology
Online Access:http://www.mdpi.com/1424-8220/16/5/709

Internet

http://www.mdpi.com/1424-8220/16/5/709

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