AAV Vectored Immunoprophylaxis for Filovirus Infections

AAV Vectored Immunoprophylaxis for Filovirus Infections

Filoviruses are among the deadliest infectious agents known to man, causing severe hemorrhagic fever, with up to 90% fatality rates. The 2014 Ebola outbreak in West Africa resulted in over 28,000 infections, demonstrating the large-scale human health and economic impact generated by filoviruses. <...

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Bibliographic Details
Main Authors: Amira D. Rghei, Laura P. van Lieshout, Lisa A. Santry, Matthew M. Guilleman, Sylvia P. Thomas, Leonardo Susta, Khalil Karimi, Byram W. Bridle, Sarah K. Wootton
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Tropical Medicine and Infectious Disease
Subjects:
monoclonal antibodies
adeno-associated virus vector
vectored-immunoprophylaxis (VIP)
vector biology
filoviruses
viral hemorrhagic fever
Online Access:https://www.mdpi.com/2414-6366/5/4/169

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https://www.mdpi.com/2414-6366/5/4/169

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