Silencing of Prrx2 Inhibits the Invasion and Metastasis of Breast Cancer both In Vitro and In Vivo by Reversing Epithelial-Mesenchymal Transition

Silencing of Prrx2 Inhibits the Invasion and Metastasis of Breast Cancer both In Vitro and In Vivo by Reversing Epithelial-Mesenchymal Transition

Background/Aims: Epithelial-mesenchymal transition (EMT) is recognized as a crucial mechanism in breast cancer progression and metastasis. Paired-related homeobox 2 (Prrx2) has been identified as a new EMT inducer in cancer, but the underlying mechanisms are still poorly understood. Methods: The exp...

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Bibliographic Details
Main Authors: Zhi-Dong Lv, Hai-Bo Wang, Xiang-Ping Liu, Li-Ying Jin, Ruo-Wu Shen, Xin-Gang Wang, Bin Kong, Hui-Li Qu, Fu-Nian Li, Qi-Feng Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Breast cancer
Epithelial-mesenchymal transition
Paired-related homeobox 2
Invasion
Proliferation
Online Access:http://www.karger.com/Article/FullText/479542

Internet

http://www.karger.com/Article/FullText/479542

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