Deciphering the mechanism of Peptostreptococcus anaerobius-induced chemoresistance in colorectal cancer: the important roles of MDSC recruitment and EMT activation

Deciphering the mechanism of Peptostreptococcus anaerobius-induced chemoresistance in colorectal cancer: the important roles of MDSC recruitment and EMT activation

Peptostreptococcus anaerobius (P. anaerobius, PA) in intestinal flora of patients with colorectal cancer (CRC) are associated with poor prognosis. Studies have shown that P. anaerobius could promote colorectal carcinogenesis and progression, but whether P. anaerobius could induce chemoresistance of...

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Bibliographic Details
Main Authors: Jinhua Gu, Xiaojun Lv, Wenwen Li, Guangcai Li, Xialian He, Ye Zhang, Lihong Shi, Xiaoqian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
Peptostreptococcus anaerobius
chemoresistance
MDSCs
IL-23
EMT
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1230681/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1230681/full

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