Investigation of synovial fluid induced Staphylococcus aureus aggregate development and its impact on surface attachment and biofilm formation.

Periprosthetic joint infections (PJIs) are a devastating complication that occurs in 2% of patients following joint replacement. These infections are costly and difficult to treat, often requiring multiple corrective surgeries and prolonged antimicrobial treatments. The Gram-positive bacterium Staph...

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Bibliographic Details
Main Authors: Matthew J Pestrak, Tripti Thapa Gupta, Devendra H Dusane, Doug V Guzior, Amelia Staats, Jan Harro, Alexander R Horswill, Paul Stoodley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231791