Compartmentalization and Trafficking in Endoplasmic Reticulum Protein Quality Control
Following translocation into the rough endoplasmic reticulum (ER), secretory proteins undergo a series of folding, maturation, compartmentalization and trafficking events. These are finely tuned to avoid misfolded protein accumulation and the consequent ER stress. Misfolded proteins and components o...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
|
Series: | Biology and Life Sciences Forum |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-9976/21/1/10 |