Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response.

Over the last decade, several studies have extensively reported that activated natural killer (NK) cells can kill autologous immature dendritic cells (DCs) in vitro, whereas they spare fully activated DCs. This led to the proposal that activated NK cells might select a more immunogenic subset of DCs...

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Bibliographic Details
Main Authors: Barbara Morandi, Lorenzo Mortara, Laura Chiossone, Roberto S Accolla, Maria Cristina Mingari, Lorenzo Moretta, Alessandro Moretta, Guido Ferlazzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22723958/?tool=EBI