Activation and Pharmacological Regulation of Inflammasomes
Inflammasomes are intracellular signaling complexes of the innate immune system, which is part of the response to exogenous pathogens or physiological aberration. The multiprotein complexes mainly consist of sensor proteins, adaptors, and pro-caspase-1. The assembly of the inflammasome upon extracel...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-07-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/12/7/1005 |