Clinical Performance of BAL Metagenomic Next-Generation Sequence and Serum (1,3)-β-D-Glucan for Differential Diagnosis of Pneumocystis jirovecii Pneumonia and Pneumocystis jirovecii Colonisation

Clinical Performance of BAL Metagenomic Next-Generation Sequence and Serum (1,3)-β-D-Glucan for Differential Diagnosis of Pneumocystis jirovecii Pneumonia and Pneumocystis jirovecii Colonisation

BackgroundDifferentiating Pneumocystis jirovecii infection from colonisation is crucial for appropriate therapy administration. In this study, we evaluated the performance of bronchoalveolar lavage fluid (BAL) metagenomic next-generation sequencing (mNGS) and serum 1,3-β-D-glucan (BDG) tests in diff...

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Bibliographic Details
Main Authors: Li Liu, Mingjuan Yuan, Yi Shi, Xin Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
mNGS
1,3-β-D-glucan
Pneumocystis jirovecii
colonisation
PJP
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.784236/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.784236/full

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