Asymmetric remote C-H borylation of internal alkenes via alkene isomerization

Sequential alkene isomerization/functionalization enables enantioselective transformations of remote C–H bonds. Here, the authors report a chiral cobalt catalytic system for the highly enantioselective, remote C–H borylation of internal alkenes via an isomerization/hydroboration sequence.

Bibliographic Details
Main Authors: Xu Chen, Zhaoyang Cheng, Jun Guo, Zhan Lu
Format: Article
Language:English
Published: Nature Portfolio 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06240-y