Extracellular Soluble Membranes from Retinal Pigment Epithelial Cells Mediate Apoptosis in Macrophages

Extracellular Soluble Membranes from Retinal Pigment Epithelial Cells Mediate Apoptosis in Macrophages

A central characterization of retinal immunobiology is the prevention of proinflammatory activity by macrophages. The retinal pigment epithelial cells (RPEs) are a major source of soluble anti-inflammatory factors. This includes a soluble factor that induces macrophage apoptosis when the activity of...

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Bibliographic Details
Main Authors: Nayan Sanjiv, Pawarissara Osathanugrah, Emma Fraser, Tat Fong Ng, Andrew W. Taylor
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
exosomes
ocular immune privilege
alpha-melanocyte-stimulating hormone
apoptosis
immune regulation
membrane FasL
Online Access:https://www.mdpi.com/2073-4409/10/5/1193

Internet

https://www.mdpi.com/2073-4409/10/5/1193

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