The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages.

The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages.

The translocator protein (TSPO) is a mitochondrial membrane protein, of as yet uncertain function. Its purported high expression on activated macrophages, has lent utility to TSPO targeted molecular imaging in the form of positron emission tomography (PET), as a means to detect and quantify inflamma...

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Bibliographic Details
Main Authors: Nehal Narayan, Harpreet Mandhair, Erica Smyth, Stephanie Georgina Dakin, Serafim Kiriakidis, Lisa Wells, David Owen, Afsie Sabokbar, Peter Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0185767

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https://doi.org/10.1371/journal.pone.0185767

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