Construction and Transfer of PEI-miRNA-126/210 Polyplex into Human Umbilical Vein Endothelial Cells with Investigation of Its Effect on Islets Survival and Function

Background: Type 1 diabetes is an autoimmune disorder characterized by the loss of pancreatic islets. Islet allotransplantation is a potentially beneficial therapeutic approach for diabetes. Islets suffer a variety of cellular insults including ischemia and partial vascular loss during isolation, re...

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Main Authors: Fatemeh Sabet Sarvestani, Ali-Mohammad Tamaddon, Mohammad-Hosein Karimi, Ramin Yaghoobi, Bita Geramizadeh, Mozhdeh Heydari, Ismail H. Al-Abdullah, Negar Azarpira
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-01-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-29-90.pdf