X-ray diffraction data for the C5a-peptidase mutant with modified activity and specificity

X-ray diffraction data for the C5a-peptidase mutant with modified activity and specificity

The Streptococcal C5a peptidase (ScpA) specifically inactivates the human complement factor hC5a, a potent anaphylatoxin recently identified as a therapeutic target for treatment of COVID-19 infections. Engineering of ScpA to enhance its potential as a therapeutic will require detailed examination o...

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Bibliographic Details
Main Authors: Todd F. Kagawa, Monica Jain, Jakki C. Cooney
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Data in Brief
Subjects:
C5a peptidase
Immunomodulatory enzymes
Exosite
Substrate binding
Enzyme activity
Mutant
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340922009817

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http://www.sciencedirect.com/science/article/pii/S2352340922009817

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