Chronic N-Acetyl-Cysteine Treatment Enhances the Expression of the Immediate Early Gene <i>Nr4a1</i> in Response to an Acute Challenge in Male Rats: Comparison with the Antidepressant Venlafaxine

Chronic N-Acetyl-Cysteine Treatment Enhances the Expression of the Immediate Early Gene <i>Nr4a1</i> in Response to an Acute Challenge in Male Rats: Comparison with the Antidepressant Venlafaxine

Despite several antidepressant treatments being available in clinics, they are not effective in all patients. In recent years, N-acetylcysteine (NAC) has been explored as adjunctive therapy for many psychiatric disorders, including depression, for its antioxidant properties. Given the promising effi...

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Bibliographic Details
Main Authors: Paola Brivio, Maria Teresa Gallo, Piotr Gruca, Magdalena Lason, Ewa Litwa, Fabio Fumagalli, Mariusz Papp, Francesca Calabrese
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
restraint
antioxidant
IEGs
neuroplastic mechanisms
rats
psychiatric disorders
Online Access:https://www.mdpi.com/1422-0067/24/8/7321

Internet

https://www.mdpi.com/1422-0067/24/8/7321

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