i4mC-GRU: Identifying DNA N4-Methylcytosine sites in mouse genomes using bidirectional gated recurrent unit and sequence-embedded features

i4mC-GRU: Identifying DNA N4-Methylcytosine sites in mouse genomes using bidirectional gated recurrent unit and sequence-embedded features

N4-methylcytosine (4mC) is one of the most common DNA methylation modifications found in both prokaryotic and eukaryotic genomes. Since the 4mC has various essential biological roles, determining its location helps reveal unexplored physiological and pathological pathways. In this study, we propose...

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Bibliographic Details
Main Authors: Thanh-Hoang Nguyen-Vo, Quang H. Trinh, Loc Nguyen, Phuong-Uyen Nguyen-Hoang, Susanto Rahardja, Binh P. Nguyen
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
DNA
N4-methylcytosine
Epigenetics
Deep learning
Bidirectional gated recurrent unit
Sequence-embedded features
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023001964

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http://www.sciencedirect.com/science/article/pii/S2001037023001964

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