Dynein Transmits Polarized Actomyosin Cortical Flows to Promote Centrosome Separation
The two centrosomes present at the onset of mitosis must separate in a timely and accurate fashion to ensure proper bipolar spindle assembly. The minus-end-directed motor dynein plays a pivotal role in centrosome separation, but the underlying mechanisms remain elusive, particularly regarding how dy...
Main Authors: | Alessandro De Simone, François Nédélec, Pierre Gönczy |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-03-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716300936 |
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