SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS

SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS

The COVID-19 is an infectious disease caused by SARS-CoV-2 infection. A large number of clinical studies found high-level expression of pro-inflammatory cytokines in patients infected with SARS-CoV-2, which fuels the rapid development of the disease. However, the specific molecular mechanism is stil...

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Bibliographic Details
Main Authors: Weiling Li, Jialu Qiao, Qiang You, Shan Zong, Qian Peng, Yuchen Liu, Song Hu, Wei Liu, Shufen Li, Xiji Shu, Binlian Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
Nsp5
MAVS
SUMOylation
NF-κB
cytokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.750969/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.750969/full

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