Membrane Activity of LL-37 Derived Antimicrobial Peptides against <i>Enterococcus hirae</i>: Superiority of SAAP-148 over OP-145

Membrane Activity of LL-37 Derived Antimicrobial Peptides against <i>Enterococcus hirae</i>: Superiority of SAAP-148 over OP-145

The development of antimicrobial agents against multidrug-resistant bacteria is an important medical challenge. Antimicrobial peptides (AMPs), human cathelicidin LL-37 and its derivative OP-145, possess a potent antimicrobial activity and were under consideration for clinical trials. In order to ove...

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Bibliographic Details
Main Authors: Paulina Piller, Heimo Wolinski, Robert A. Cordfunke, Jan Wouter Drijfhout, Sandro Keller, Karl Lohner, Nermina Malanovic
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomolecules
Subjects:
antimicrobial peptides (AMPs)
membrane-peptide interaction
antimicrobial activity
phospholipids
membrane permeability
membrane depolarization
Online Access:https://www.mdpi.com/2218-273X/12/4/523

Internet

https://www.mdpi.com/2218-273X/12/4/523

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