Exercise preconditioning inhibits doxorubicin-induced cardiotoxicity via YAP/STAT3 signaling

Exercise preconditioning inhibits doxorubicin-induced cardiotoxicity via YAP/STAT3 signaling

Doxorubicin (DOX) possesses strong anti-tumor effects but is limited by its irreversible cardiac toxicity. The relationship between exercise, a known enhancer of cardiovascular health, and DOX-induced cardiotoxicity has been a focus of recent research. Exercise has been suggested to mitigate DOX...

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Bibliographic Details
Main Authors: Chuan-Zhi Wang, Heng-Zhi Guo, Jing-Zhi Leng, Zhi-De Liang, Jing-Tai Wang, Li-Jie Luo, Shi-Qiang Wang, Yang Yuan
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Exercise preconditioning
Doxorubicin
Cardiotoxicity
YAP
STAT3
Cardiac protection
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024030664

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024030664

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