Research Progress and Prospects of Isocitrate Dehydrogenase Gene Mutation in Chondrosarcoma
Isocitrate dehydrogenase (IDH) is the more mutation-prone human metabolic gene. In the presence of nicotinamide adenine dinucleotide phosphate (NADPH), mutant IDH can bind to α-ketoglutaric acid (α-KG) and reduce it to 2-hydroxyglutaric acid (2-HG), participating in various bio...
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| Format: | Article |
| Language: | zho |
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Chinese General Practice Publishing House Co., Ltd
2024-04-01
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| Series: | Zhongguo quanke yixue |
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| Online Access: | https://www.chinagp.net/fileup/1007-9572/PDF/20230284.pdf |