A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects

A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects

Background: Our previous in vitro results demonstrated that 11-dehydrosinulariolide significantly reduced 6-hydroxydopamine-induced cytotoxicity and apoptosis in a human neuroblastoma cell line, SH-SY5Y, and suppressed the expression of inducible NO synthase (iNOS) and cyclooxygenase 2 in lipopolysa...

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Bibliographic Details
Main Authors: Chun-Hong Chen, Nan-Fu Chen, Chien-Wei Feng, Shu-Yu Cheng, Han-Chun Hung, Kuan-Hao Tsui, Chi-Hsin Hsu, Ping-Jyun Sung, Wu-Fu Chen, Zhi-Hong Wen
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Marine Drugs
Subjects:
Sinularia flexibilis
marine natural compound
11-dehydrosinulariolide
microglia
neuroprotection
spinal cord injury
anti-inflammation
Online Access:http://www.mdpi.com/1660-3397/14/9/160

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http://www.mdpi.com/1660-3397/14/9/160

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