Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to <i>Onchocerca volvulus</i> in Mice and Non-Human Primates

Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to <i>Onchocerca volvulus</i> in Mice and Non-Human Primates

Onchocerciasis remains a debilitating neglected tropical disease. Due to the many challenges of current control methods, an effective vaccine against the causative agent <i>Onchocerca volvulus</i> is urgently needed. Mice and cynomolgus macaque non-human primates (NHPs) were immunized wi...

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Bibliographic Details
Main Authors: Nathan M. Ryan, Jessica A. Hess, Erica J. Robertson, Nancy Tricoche, Cheri Turner, Jenn Davis, Nikolai Petrovsky, Melissa Ferguson, William J. Rinaldi, Valerie M. Wong, Ayako Shimada, Bin Zhan, Maria Elena Bottazzi, Benjamin L. Makepeace, Sean A. Gray, Darrick Carter, Sara Lustigman, David Abraham
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Vaccines
Subjects:
<i>Onchocerca volvulus</i>
vaccine
durability
adjuvant
mice
non-human primates
Online Access:https://www.mdpi.com/2076-393X/11/7/1212

Internet

https://www.mdpi.com/2076-393X/11/7/1212

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